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OCR: n of Proposed explanations for the suppress a include gonadal function in hyperprolactinaem inhibition suppression of gonadotrophin secretion sing of positive oestrogen feedback on luteir ncrease in hormone (LH) secretion in women; an e of the adrenal androgen secretion; and blocka evel (Fig. effects of gonadotrophins at the gonada chanism is 4.18). It is probable that an important m which prolactin feedback at the hypothalamus ng alters secretion of gonadotrophin-releas hormone (GnRH), thus causing LH and etion to follicle-stimulating hormone (FSH) sec onadal become inappropriately low, relative to atility also steroid levels. Abnormalities in LH pul nd FSH occur, Prolactin may interfere with LH e action at the gonad, blocking progestero drogen synthesis, and may stimulate adrenal a segre ...